Spider

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 "Well, maybe you'll just have to make your own world wide web." 

Spiders work well for a kiting melee style. Retreat with Fleet-Footed, trap your pursuers with Web Weaver, and dispatch them with Folding Fangs and Strongly Venomous. Full Night Vision and Infrared Vision put you in charge of the nighttime battlefield.

The threshold mutation of this category is called Arachnid ingame.

Traits

Fleet-Footed FLEET Possible Starting Trait SPIDER MOUSE
Cancels: Slow Footed, Road-Runner, Ponderous, Very Ponderous, Extremely Ponderous
Changes to: Road-Runner
Point cost: 2
"You can move more quickly than most, resulting in a 15% speed bonus on sure footing."
Poison Resistant POISRESIST Possible Starting Trait INSECT SLIME SPIDER MEDICAL
Leads to: Intestinal Fortitude
Point cost: 1
"Your system is rather tolerant of poisons and toxins, and most will affect you less."

Normal Mutations

Full Night Vision NIGHTVISION3 FISH TROGLOBITE SPIDER
Requires: High Night Vision
Cancels: Fey Vision, Fey Nightsight, Feline Vision, Ursine Vision
Leads to: Infrared Vision
Point cost: 6
"You can see in pitch blackness as if you were wearing night-vision goggles. Activate to toggle NV-visible areas on or off."
Infrared Vision INFRARED INSECT TROGLOBITE SPIDER
Requires: Full Night Vision
Cancels: Reptilian IR
Point cost: 5
"Your eyes have mutated to pick up radiation in the infrared spectrum."
Lightly Furred LIGHTFUR SPIDER CHIMERA MOUSE
Requires: Rough Skin
Cancels: Rough Skin, Scales, Thick Scales, Sleek Scales, Feathers, Down, Furry, Shaggy Fur, Gray Fur, Sleek Fur, Lynx Fur, Chitinous Skin, Chitinous Armor, Chitinous Plate, Hairy Chitin, Furred Chitin, Furred Plate, Phelloderm, Bark
Changes to: Furry, Sleek Fur, Gray Fur, Shaggy Fur, Hairy Chitin
Point cost: 1 / Visibility: 6 / Ugliness: 2
"Light fur has grown to cover your entire body, providing slight protection from cold."
Chitinous Skin CHITIN SPIDER
Requires: Rough Skin
Cancels: Rough Skin, Scales, Thick Scales, Sleek Scales, Feathers, Down, Lightly Furred, Furry, Shaggy Fur, Gray Fur, Sleek Fur, Lynx Fur, Chitinous Armor, Chitinous Plate, Hairy Chitin, Furred Chitin, Furred Plate, Phelloderm, Bark
Changes to: Chitinous Armor, Hairy Chitin
Point cost: 2 / Visibility: 3 / Ugliness: 2
"Your epidermis has turned into a thin, flexible layer of chitin. It provides minor protection from cutting wounds. Slightly reduces wet effects."
Chitinous Plate CHITIN3 SPIDER
Requires: Chitinous Armor, Furred Chitin
Cancels: Rough Skin, Scales, Thick Scales, Sleek Scales, Feathers, Down, Lightly Furred, Furry, Shaggy Fur, Gray Fur, Sleek Fur, Lynx Fur, Chitinous Skin, Chitinous Armor, Hairy Chitin, Furred Chitin, Furred Plate, Phelloderm, Bark
Changes to: Furred Plate
Point cost: 2 / Visibility: 8 / Ugliness: 5
"You've grown a chitin exoskeleton made of thick, stiff plates. It provides excellent physical protection, make your punches hit harder but reduces your Dexterity by 1 and encumbers all body parts but your eyes and mouth. Greatly reduces wet effects."
Hairy Chitin CHITIN_FUR SPIDER
Requires: Chitinous Skin, Lightly Furred
Cancels: Rough Skin, Scales, Thick Scales, Sleek Scales, Feathers, Down, Lightly Furred, Furry, Shaggy Fur, Gray Fur, Sleek Fur, Lynx Fur, Chitinous Skin, Chitinous Armor, Chitinous Plate, Furred Chitin, Furred Plate, Phelloderm, Bark
Changes to: Furred Chitin
Point cost: 3 / Visibility: 10 / Ugliness: 4
"You've developed some sort of hair growing out of your chitin. It's a bit warmer than not having hair."
Furred Chitin CHITIN_FUR2 SPIDER
Requires: Hairy Chitin
Cancels: Rough Skin, Scales, Thick Scales, Sleek Scales, Feathers, Down, Lightly Furred, Furry, Shaggy Fur, Gray Fur, Sleek Fur, Lynx Fur, Chitinous Skin, Chitinous Armor, Chitinous Plate, Hairy Chitin, Furred Plate, Phelloderm, Bark
Changes to: Furred Plate, Chitinous Plate
Point cost: 4 / Visibility: 10 / Ugliness: 4
"Your chitin hair has thickened and spread across your body. It provides minor warmth and helps you sense nearby vibrations."
Venomous POISONOUS SLIME TROGLOBITE SPIDER
Requires: Poison Resistant
Changes to: Strongly Venomous
Leads to: Intestinal Fortitude
Point cost: 1
"Your body produces a potent venom. Cutting or stabbing attacks from mutations have a chance to poison your target."
Mandibles MANDIBLES INSECT SPIDER
Requires: Mouth Flaps
Cancels: Mouth Tentacles, Fangs, Incisors, Saber Teeth, Folding Fangs, Proboscis, Beak, Woodpecker Beak, Hummingbird Beak, Shark Teeth, Folding Fangs, Bovine Snout, Lupine Muzzle, Ursine Muzzle, Rodent Muzzle, Reptilian Muzzle, Proboscis, Beak, Woodpecker Beak, Hummingbird Beak
Changes to: Folding Fangs
Point cost: 1 / Visibility: 8 / Ugliness: 6
"A set of insect-like mandibles have grown around your mouth. They allow you to eat faster and provide a slicing unarmed attack, but prevent wearing mouthwear. Slightly reduces wet effects."
Web Walker WEB_WALKER SPIDER
Leads to: Web Weaver
Point cost: 1
"Your body excretes very fine amounts of a chemical which prevents you from sticking to webs. Walking through webs does not affect you at all."
Very Dextrous DEX_UP_2 LIZARD SPIDER CHIMERA RAPTOR MOUSE
Requires: Dextrous
Changes to: Extremely Dextrous
Point cost: 2
"You are nimbler. Dexterity + 2"
Light Sensitive TROGLO LIZARD BEAST INSECT SLIME SPIDER
Cancels: Sunlight Dependent
Changes to: Very Light Sensitive
Point cost: -2
"Sunlight makes you uncomfortable. If you are outdoors and the weather is Sunny, you suffer -1 to all stats."
Carnivore CARNIVORE LIZARD BEAST FELINE SPIDER CHIMERA RAPTOR
Cancels: Meat Intolerance, Herbivore, Ruminant, Grazer
Leads to: Saprovore
Point cost: -4
"Your body's ability to digest fruits, vegetables, grains and nuts is severely hampered. You cannot eat anything besides meat."
Heat Dependent COLDBLOOD FISH CEPHALOPOD SPIDER
Cancels: Light Eater, Hyper-Metabolism, Fast Metabolism, Very Fast Metabolism, Extreme Metabolism, Very Heat Dependent, Cold Blooded, Ectothermic
Changes to: Very Heat Dependent
Point cost: 0
"Your muscle response is dependent on ambient temperatures. You lose 1% of your speed for every 5 (2.8) degrees below 65 F (18.3 C). This sluggishness helps you conserve energy, however."

Post-threshold mutations

Furred Plate CHITIN_FUR3 Threshold Mutation SPIDER
Requires: Furred Chitin, Chitinous Plate
Cancels: Rough Skin, Scales, Thick Scales, Sleek Scales, Feathers, Down, Lightly Furred, Furry, Shaggy Fur, Gray Fur, Sleek Fur, Lynx Fur, Chitinous Skin, Chitinous Armor, Chitinous Plate, Hairy Chitin, Furred Chitin, Phelloderm, Bark
Point cost: 5 / Visibility: 10 / Ugliness: 4
"Your exoskeleton has hardened considerably--restricting movement, granted--and boasts a fine coat of hairs that put feline whiskers to shame."
Urticating Hairs CF_HAIR Threshold Mutation SPIDER
Requires: Furred Chitin, Furred Plate
Point cost: 3 / Visibility: 1 / Ugliness: 1
"Significant amounts of your hairs have loosened. If some creature tries to attack you, your assailant is quite likely to get fine, bristly chitin in an irritating spot; it doesn't carry your venom but it will be distracting."
Strongly Venomous POISONOUS2 Threshold Mutation SPIDER
Requires: Venomous
Point cost: 2
"Your venom has become particularly strong. You're confident that your bites or other cutting/stabbing natural attacks will take your target down quickly."
Culler PRED1 Not purifiable Threshold Mutation LIZARD BEAST FELINE LUPINE URSINE SPIDER CHIMERA RAPTOR
Requires: Carnivore, Bear
Cancels: Pacifist
Changes to: Hunter
Point cost: 2
"You've had a revelation: by killing the weaker creatures, who would only die anyway, you preserve resources for those better able to survive. You are less bothered by the deaths of others: their own weakness invited these fates upon them."
Hunter PRED2 Not purifiable Threshold Mutation LIZARD BEAST FELINE LUPINE URSINE SPIDER CHIMERA RAPTOR
Requires: Carnivore, Bear
Additional requirement: Culler
Cancels: Pacifist
Changes to: Predator
Point cost: 3
"Your brain has a lot more in common with a predatory animal than a human, making it easier to control misplaced reactions to the death of your prey. Additionally, combat skills, which you use to hunt, are easier to learn and maintain."
Predator PRED3 Targeted Mutation Only Not purifiable Threshold Mutation LIZARD BEAST FELINE LUPINE URSINE SPIDER CHIMERA RAPTOR
Requires: Carnivore, Bear
Additional requirement: Hunter
Cancels: Pacifist
Changes to: Apex Predator
Leads to: Sapiovore
Point cost: 3
"You consider yourself something other than human and no longer empathize with them. Combat skills are easy to learn and maintain, but your critical thinking, so characteristic to these creatures, suffers."
Sapiovore SAPIOVORE Targeted Mutation Only Not purifiable Threshold Mutation LIZARD BEAST URSINE SPIDER CHIMERA RAPTOR
Requires: Carnivore
Additional requirement: Predator, Apex Predator
Point cost: 1
"The hairless apes make as good eating as any other meat."
Folding Fangs FANGS_SPIDER Threshold Mutation SPIDER
Requires: Mandibles
Additional requirement: Venomous, Strongly Venomous
Cancels: Mouth Tentacles, Fangs, Incisors, Saber Teeth, Mandibles, Proboscis, Beak, Woodpecker Beak, Hummingbird Beak, Shark Teeth, Mandibles, Bovine Snout, Lupine Muzzle, Ursine Muzzle, Rodent Muzzle, Reptilian Muzzle, Proboscis, Beak, Woodpecker Beak, Hummingbird Beak
Point cost: 2 / Visibility: 6 / Ugliness: 6
"Your mandibles have developed extensible fangs, allowing you to bite quickly or ensure your venom goes home, as desired."
Web Spinner WEB_SPINNER Threshold Mutation SPIDER
Requires: Web Walker
Cancels: Slimy
Changes to: Web Weaver
Point cost: -3
"Your body produces and anchors webbing. Too bad you can't seem to control the process. There is a chance that you will leave webs in your wake."
Web Weaver WEB_WEAVER Threshold Mutation SPIDER
Requires: Web Spinner
Cancels: Slimy
Point cost: 2
"You've developed the necessary anatomy and techniques to control your web-generation. Activate this to start or stop weaving webs."
Web Diver WEB_RAPPEL Threshold Mutation SPIDER
Requires: Web Weaver
Point cost: 2
"Your webbing is easily strong enough to support your weight. You'll use it to descend down any sheer drops you may encounter."
Rope Webs WEB_ROPE Threshold Mutation SPIDER
Requires: Web Weaver
Point cost: 3
"With spinnerets like THESE, who needs rope?! Activate to produce rope."
Insect Limbs INSECT_ARMS Not purifiable Threshold Mutation INSECT SPIDER
Requires: Chitinous Skin, Chitinous Armor, Chitinous Plate, Furred Chitin, Furred Plate
Additional requirement: Antennae
Cancels: Paws, Broad Paws, Insect Arms, Arachnid Limbs, Arachnid Arms, Tentacle Arms, 4 Tentacles, 8 Tentacles
Changes to: Insect Arms, Arachnid Limbs
Point cost: -5 / Visibility: 8 / Ugliness: 5
"You've *finally* sprouted a pair of arms from your midsection. They flail more-or-less uncontrollably, making you feel rather larval."
Arachnid Limbs ARACHNID_ARMS Targeted Mutation Only Not purifiable Threshold Mutation SPIDER
Requires: Insect Limbs
Additional requirement: Chitinous Plate, Furred Chitin, Furred Plate
Cancels: Paws, Broad Paws, Insect Limbs, Insect Arms, Arachnid Arms, Tentacle Arms, 4 Tentacles, 8 Tentacles
Changes to: Arachnid Arms
Point cost: -7 / Visibility: 10 / Ugliness: 10
"There's the last two limbs you were expecting. Unfortunately you still can't coordinate them, so you're getting in your own way. A lot."
Arachnid Arms ARACHNID_ARMS_OK Targeted Mutation Only Not purifiable Threshold Mutation SPIDER
Requires: Arachnid Limbs
Additional requirement: Venomous, Strongly Venomous, Web Diver
Cancels: Paws, Broad Paws, Insect Limbs, Insect Arms, Arachnid Limbs, Tentacle Arms, 4 Tentacles, 8 Tentacles
Point cost: 0 / Visibility: 6 / Ugliness: 10
"You have four handsome limbs, and then those mutant 'hand' and 'foot' things. They probably aren't worth concealing."

Notes

You need to make a nest with "thick webs" (the kind that blocks line-of-sight) to be able to sleep. Activate Web Weaver, and then pause on the same tile at least three turns to make cobwebs -> webs -> thick webs.